If you have spent any time reading about cosmetic injectables recently, you have almost certainly come across Rejuran Healer. Originally developed in South Korea, where it has been a cornerstone of skin rejuvenation clinics since 2014, Rejuran Healer has rapidly become one of the most talked-about treatments in Melbourne clinics over the past two years. But why is it generating so much attention, and how does it actually differ from the skin booster injections most people are already familiar with?
This guide explores the science behind the treatment, what makes it genuinely different from traditional skin boosters, which formulations target which concerns, and what to expect from the treatment journey, including that question everyone asks about the bumps.
What Is Rejuran Healer?
Rejuran is a polynucleotide treatment, a class of injectable that works by delivering biologically active DNA molecules directly into the dermis. These molecules are derived from the DNA of wild salmon, purified through an advanced extraction process to produce a material that is highly biocompatible with human tissue.
Unlike treatments that add volume or fill a space in the skin, Rejuran Healer works at a cellular level. The polynucleotides stimulate fibroblasts, the cells responsible for collagen production, encouraging the skin to repair and regenerate itself rather than simply masking signs of ageing or damage. The result is genuine structural improvement in skin quality: better texture, improved elasticity, stronger hydration retention, and a reduction in the visibility of fine lines and superficial scarring.
Rejuran received TGA approval in Australia in July 2023, and since then demand at Melbourne clinics like Victorian Laser and Skin Clinic has grown significantly, particularly among patients seeking a treatment that delivers lasting skin quality improvements rather than a temporary cosmetic fix.
Rejuran vs Skin Boosters: What Is the Difference?
This is the question at the heart of the Rejuran conversation, and it is worth answering clearly.
Traditional skin booster injections, such as hyaluronic acid-based boosters, work primarily through hydration. Hyaluronic acid is a naturally occurring sugar molecule with an exceptional capacity to attract and bind water. When injected superficially into the skin, it plumps and hydrates the tissue, improving the appearance of dullness and fine lines. The effect is real, but it is hydration-driven rather than regenerative, and it is temporary.
Rejuran vs skin boosters is therefore not a comparison of two similar things done differently. It is a comparison of two fundamentally different biological mechanisms. Rejuran does not hydrate by attracting water. It repairs and stimulates. The polynucleotides interact directly with the skin’s cells, promoting collagen synthesis, reducing inflammation, supporting wound healing, and improving the skin’s overall structural integrity over time.
A useful way to think about it: skin boosters give your skin a drink of water. Rejuran Healer encourages your skin to start repairing and rebuilding its own foundations. Both have a place in a comprehensive skin programme, but they are solving different problems.
The Science: What Polynucleotides Actually Do
Polynucleotides are long-chain DNA fragments. When introduced into the dermis through skin healing injections, they act on the skin in several ways simultaneously.
First, they bind to fibroblast receptors and stimulate these cells to increase their production of collagen and elastin, two of the proteins most responsible for skin firmness and resilience. Second, they have documented anti-inflammatory properties, which makes them particularly valuable for skin that has been damaged by acne, sun exposure, or environmental stressors. Third, polynucleotides provide a structural scaffold within the dermis, supporting the architecture of the skin from within rather than simply filling a space.
This combination of regeneration, inflammation control, and structural support is what distinguishes Rejuran Healer from most other injectables currently available, and it explains why the treatment has attracted such sustained interest from both clinicians and patients seeking genuine skin quality improvement.
Which Rejuran Formulation Is Right for You?
Not all Rejuran products are the same. Victorian Laser and Skin Clinic offers three formulations, each designed for a specific set of concerns.
Rejuran Classic is the full-face formulation and the most widely used. Delivered across the face using a series of micro-injections, it addresses overall skin quality, improving texture, hydration retention, fine lines, and general luminosity. It is the most appropriate starting point for most patients looking to improve their skin health comprehensively.
Rejuran-I (eye) is a lower-viscosity formulation designed specifically for the delicate skin around the eye area. This is one of the thinnest, most fragile areas of facial skin, and it is typically the first to show signs of ageing, including fine lines, crepiness, and dark circles. Rejuran-I is injected with particular precision to thicken and repair this tissue without disrupting the natural appearance of the eye contour.
Rejuran-S (scar) is a higher-viscosity, more concentrated formulation designed to target acne scars and other superficial scarring. It works by stimulating collagen remodelling specifically within the scar tissue, gradually smoothing and reducing the depth of atrophic scarring over a course of treatments.
For many patients, combining formulations within a treatment plan, for example using Rejuran Classic across the full face with Rejuran-S targeted at specific acne scarring, delivers the most comprehensive outcome. Your treating clinician will assess your skin and recommend the appropriate approach during your initial consultation.
Rejuran Healer in Melbourne: The Treatment Journey and Cost
At Victorian Laser and Skin Clinic, every Rejuran treatment begins with a complimentary consultation. Your clinician will assess your skin quality, discuss your concerns and goals, and recommend the appropriate formulation and treatment schedule.
The treatment itself involves a series of precise micro-injections administered across the target area using a fine needle. A topical anaesthetic is applied beforehand to ensure comfort. Most treatment sessions take between 30 and 45 minutes. You can return to your normal daily activities immediately afterwards, though a few post-treatment precautions apply (see below).
For optimal results, an initial course of two to three sessions spaced approximately one month apart is recommended. Improvements in skin texture and quality begin to become visible at two to four weeks following each session, with the most significant results developing progressively across the treatment course. Maintenance sessions three to four times per year help sustain the improvements long-term.
Rejuran healer cost at Victorian Laser and Skin Clinic starts from $600 per session. For full current pricing across all formulations and package options, visit our Rejuran treatment page.
Many patients who explore Rejuran in Melbourne also ask about combining it with other treatments for enhanced results. Rejuran pairs particularly well with anti-wrinkle injections and masseter injections as part of a comprehensive facial rejuvenation plan, with the treatments addressing complementary concerns at different layers of the skin and soft tissue.
Post-Treatment: What Are the Bumps, and How Long Do They Last?
This is the question almost every new Rejuran Healer patient asks, and it deserves a clear, honest answer.
Immediately after treatment, small raised bumps or papules are visible at each injection site across the treated area. These look similar to insect bites and are a completely normal and expected response to the micro-injections. They are the product sitting just beneath the skin surface before it integrates into the tissue. In the vast majority of cases, these papules resolve within 24 to 36 hours. Some mild redness, minor bruising, and skin sensitivity may also occur and typically settle within one to three days.
Post-treatment, your clinician will advise you to avoid high-heat environments such as saunas and steam rooms, refrain from strenuous exercise for 24 hours, and hold off on active skincare ingredients such as vitamin A and C for three days. Broad-spectrum SPF 50+ sunscreen is strongly recommended daily to protect the skin during the recovery period and beyond.
The post-treatment appearance is temporary and predictable. Most patients schedule their Rejuran sessions a few days before any major social commitments, rather than immediately before, to allow the skin to settle fully.
Frequently Asked Questions
Is Rejuran Healer the same as a filler? No. Rejuran Healer does not add volume to the face and is not designed to fill or plump specific features. It is a skin healing injectable that works at a cellular level to stimulate collagen production and improve skin quality from within. It is a fundamentally different product to dermal filler.
What is the salmon DNA in Rejuran? Is it safe? The polynucleotides in Rejuran are derived from the DNA of wild salmon, purified through an advanced extraction and filtration process to remove all proteins that could trigger an immune or allergic response. What remains is a chain of DNA fragments that are highly biocompatible with human tissue. More than ten million syringes have been administered globally with no major adverse events relating to blood vessel blockage reported.
How soon will I see results from Rejuran Healer? Initial improvements in skin texture and hydration are typically visible at two to four weeks after the first session. More meaningful changes in skin quality, including visible improvements to fine lines and surface scarring, develop progressively across a course of two to three treatments. The skin continues to respond and improve for several weeks after each session as collagen production increases.
Can Rejuran Healer be combined with other treatments? Yes, and for many patients a combined approach delivers the best overall outcome. Rejuran works well alongside anti-wrinkle injections, dermal filler, and energy-based treatments such as skin needling or laser. Your clinician will advise on timing and sequencing to ensure treatments complement rather than interfere with one another.
Who is not suitable for Rejuran Healer? Rejuran Healer is not recommended during pregnancy or breastfeeding, for patients with known allergies to salmon or fish-derived products, or for individuals with active skin infections in the treatment area. A full medical history and skin assessment at your consultation will confirm your suitability for treatment.
Ready to explore Rejuran Healer in Melbourne? Book your complimentary consultation with the team at Victorian Laser and Skin Clinic across our Melbourne CBD, Hawthorn, Mount Waverley, and Viewbank locations. Visit our Rejuran treatment page for full pricing details, or explore our complete range of cosmetic injectables to build a treatment plan tailored to your skin goals.
